Goose astrovirus (GAstV) is a small, non-enveloped, single-stranded, positive sense RNA virus. Since 2016, GAstV has rapidly spread in various regions of China. In Sichuan, from 2019 to 2022, out of 113 samples collected from infected goslings, 97 were tested positive for GAstV through PCR. Significantly, In the past three years in Sichuan, the outbreak of GAstV accounted for 85.8% of all goose-origin viruses. Among these cases, 63.9% of the cases were single infection with the GAstV, 29.9% were mixed infection with one other kind of waterfowl virus, and 6.2% were mixed infection with three other kinds of waterfowl viruses. In order to further compare the differences in virulence of different strains isolated. Our research isolated 12 representative strains of single infection with GAstV. The related research is titled "Molecular epidemiology and virulence of goose astroviruses genotype-2 with different internal gene sequences " and was published in the Frontiers in Microbiology on December 7, 2023 (DOI: 10.3389/fmicb. 2023, 1301861). 

The first author of the paper is Linhua Xu, and the corresponding authors are Pr AnChun Cheng and Pr Shun Chen. This research was supported by the National Key Research and Development Program of China [grant number 2022YFD1801900], National Natural Science Foundation of China [grant number 32272976], Sichuan Provincial Department of science and technology international scientific and technological innovation cooperation [grant number 2022YFH0026], the earmarked fund for China Agriculture Research System [grant number CARS-42-17], and the Program Sichuan Veterinary Medicine and Drug Innovation Group of China Agricultural Research System [grant number SCCXTD-2021-18].