Full name: Renyong Jia
Title/Position: Professor/Vice dean
Contact Address: 7-1118
Email Address: jiary@sicau.edu.cn
Education Background and Working Experience:
Education:
Veterinary Public Health, Sichuan Agricultural University, Bachelor, July 1992.
Preventive Veterinary Medicine, Sichuan Agricultural University, PhD, June 2008.
Work experience:
1992.07-2002.08: Southwest University (former name: Sichuan Animal Husbandry and Veterinary College).
2002.09-2005.05: Southwest University (former name: Southwest Agricultural University).
2005.06-Present: College of Veterinary Medicine, Sichuan Agricultural University.
Research direction:
1. Apoptosis process induced by DTMUV infection.
2. MiRNA modulate viral replication.
3. Novel vaccine development.
Scientific research projects:
1. National Natural Science Foundation of China: The mechanism of miRNA-148a-5p targeting SOCS1 in mediating duck tembusu virus evasion of host innate immunity, 2021, Host.
2. National Natural Science Foundation of China: The mechanism of duck tembusu virus attenuated by 2'-O methyltransferase deficiency, 2018, Host.
3. Science and Technology Planning Project of Sichuan province: Molecular mechanism of apoptosis by duck tembusu virus NS3 protein in DEFs, 2022, Host.
4. Science and Technology Planning Project of Sichuan province (Key projects): Studying the expression profiles of miRNAs encoding by duck enteritis virus and their role in virus infection and replication, 2017, Host.
Honorary awards:
1. Second Prize of National Technology Invention, Ministry of Science and Technology, 2013.
2. Shennong China Agricultural Science and Technology Award Outstanding Innovation Team Award, Ministry of Agriculture and Rural Affairs, 2019.
3. Second Prize of Sichuan Province Science and Technology Progress Award, Sichuan Provincial People's Government, 2017.
4. Third Prize of Sichuan Province Science and Technology Progress Award, Sichuan Provincial People's Government, 2012.
Academic Achievements:
1. Huang S, Huang J, Cui M, Wu X, Wang M, Zhu D, Chen S, Liu M, Zhao X, Wu Y, Yang Q, Zhang S, Ou X, Mao S, Gao Q, Yu Y, Tian B, Liu Y, Zhang L, Yin Z, Jing B, Chen X, Cheng A*, Jia R*. Duck Tembusu Virus Inhibits Type I Interferon Production through the JOSD1-SOCS1-IRF7 Negative-Feedback Regulation Pathway [J]. J Virol. 2022, 96(18):e0093022.
2. Pan Y, Cai W, Cheng A*, Wang M, Yin Z, Jia R*. Flaviviruses: Innate Immunity, Inflammasome Activation, Inflammatory Cell Death, and Cytokines [J]. Front Immunol. 2022, 13:829433.
3. Wu X, Pan Y, Huang J, Huang S, Wang M, Chen S, Liu M, Zhu D, Zhao X, Wu Y, Yang Q, Zhang S, Ou X, Zhang L, Liu Y, Yu Y, Gao Q, Mao S, Sun D, Tian B, Yin Z, Jing B, Cheng A, Jia R*. The substitution at residue 218 of the NS5 protein methyltransferase domain of Tembusu virus impairs viral replication and translation and may triggers RIG-I-like receptor signaling [J]. Poult Sci. 2022, 101(9):102017.
4. Cai W, Pan Y, Cheng A*, Wang M, Yin Z, Jia R*. Regulatory Role of Host MicroRNAs in Flaviviruses Infection [J]. Front Microbiol. 2022, 13:869441.
5. Pan Y, Cai W, Cheng A*, Wang M, Chen S, Huang J, Yang Q, Wu Y, Sun D, Mao S, Zhu D, Liu M, Zhao X, Zhang S, Gao Q, Ou X, Tian B, Yin Z, Jia R*. Duck Tembusu virus infection induces mitochondrial-mediated and death receptor-mediated apoptosis in duck embryo fibroblasts [J]. Vet Res. 2022, 53(1):53.
6. Zhang X, Zhang Y, Jia R*, Wang M, Yin Z, Cheng A*. Structure and function of capsid protein in flavivirus infection and its applications in the development of vaccines and therapeutics [J]. Vet Res. 2021, 52(1):98.
7. Xu D, Li C, Liu G, Chen Z, Jia R*. Generation and evaluation of a recombinant goose origin Newcastle disease virus expressing Cap protein of goose origin avastrovirus as a bivalent vaccine in goslings [J]. Poult Sci. 2019, 98(10):4426-4432.
8. Zhang X, Jia R*, Pan Y, Wang M, Chen S, Zhu D, Liu M, Zhao X, Yang Q, Wu Y, Zhang S, Liu Y, Zhang L, Yin Z, Jing B, Huang J, Tian B, Pan L, Yu Y, Ur Rehman M, Cheng A*. Therapeutic effects of duck Tembusu virus capsid protein fused with staphylococcal nuclease protein to target Tembusu infection in vitro [J]. Vet Microbiol. 2019, 235:295-300.
9. Huang J, Yang C, Jia R*, Wang M, Chen S, Liu M, Zhu D, Zhao X, Yang Q, Wu Y, Zhang L, Yin Z, Jing B, Cheng A*. Induction of a protective response in ducks vaccinated with a DNA vaccine encoding engineered duck circovirus Capsid protein [J]. Vet Microbiol. 2018, 225:40-47.
10. Yu X, Jia R*, Huang J, Shu B, Zhu D, Liu Q, Gao X, Lin M, Yin Z, Wang M, Chen S, Wang Y, Chen X, Cheng A*. Attenuated Salmonella typhimurium delivering DNA vaccine encoding duck enteritis virus UL24 induced systemic and mucosal immune responses and conferred good protection against challenge [J]. Vet Res. 2012, 43(1):56.
