Full name: Mafeng Liu
Title/Position: Professor/Associate director
Contact Address: 211# Huimin Road, Wenjiang district, Chengdu.
Email Address: liumafengra@163.com
Education Background and Working Experience:
2021.01-now, Professor, College of veterinary medicine, Sichuan Agricultural University
2013.02-2020.12, associate professor, College of veterinary medicine, Sichuan Agricultural University
2009.03-2012.09,Ph.D., life sciences, University of Paris VI, France
Research direction: Veterinary microbiology
Personal profile:
Scientific research projects :
1. National Natural Science Foundation of China: a novel hemophore mediated heme uptake mechanism of Riemerella anatipestifer (3217190300), 2022-2025.
2. National Natural Science Foundation of China: Discovery and function research of HmuY-like protein and its receptor of Riemerella anatipestifer (31772772) 2018-2021, with a project fund of 610000.
3. Sichuan International Science and technology cooperation and exchange research 2016-2019.
4. China Postdoctoral Science Foundation (2014M552378) 2014.
5. Doctoral Program Fund of the Ministry of Education (20135103120006) 2014-2017.
6. The National Natural Science Foundation of China (31302131) (2014 to 2017).
Honorary awards:
1. Second prize of Sichuan Provincial Science and Technology award.
2. "Shennong China Agricultural Science and Technology Award" (excellent innovation team award) of the Ministry of agriculture.
Academic Achievements:
1. Main works: 《Duck plague》co-editor
2. Representative articles
3. 1. Mi Huang#, Mafeng Liu#, Li Huang, Mingshu Wang, Renyong Jia, Dekang Zhu, Shun Chen, Xinxin Zhao, Shaqiu Zhang, Qun Gao, Ling Zhang, Anchun Cheng*. The activation and limitation of the bacterial natural transformation system: The function in genome evolution and stability[J]. Microbiol Res, 2021 Aug 24;252:126856.
4. 2. Li Zhang, Li Huang, Mi Huang, Mengying Wang, Dekang Zhu, Mingshu Wang, Renyong Jia, Shun Chen, Xinxin Zhao, Qiao Yang, Ying Wu, Shaqiu Zhang, Juan Huang, Xumin Ou, Sai Mao, Qun Gao, Bin Tian, Anchun Cheng, Mafeng Liu*. Effect of Nutritional Determinants and TonB on the Natural Transformation of Riemerella anatipestifer[J]. Front Microbiol, 2021 Aug 10;12:644868.
5. 3. Liu M, Liu S, Huang M, Wang Y, Wang M, Tian X, Li L, Yang Z, Wang M, Zhu D, Jia R, Chen S, Zhao X, Yang Q, Wu Y, Zhang S, Huang J, Ou X, Mao S, Gao Q, Sun D, Yu Y, Cheng A. An exposed outer membrane haemin-binding protein facilitates haemin transport by a TonB-dependent receptor in Riemerella anatipestifer. Appl Environ Microbiol. 2021 May 14:AEM.00367-21.
6. 4. Liu M, Huang M, Wang M, Zhu D, Jia R, Chen S, Zhang L, Pan L and Cheng A. The Clustered Regularly Interspaced Short Palindromic Repeat System and Argonaute: An Emerging Bacterial Immunity System for Defense Against Natural Transformation? [J]. Front. Microbiol., 22 October 2020.
7. 5. Tian X, Huang L, Wang M, Biville F, Zhu D, Jia R, Chen S, Zhao X, Yang Q, Wu Y, Zhang S, Huang J, Zhang L, Yu Y, Cheng A, Liu M*. The functional identification of Dps in oxidative stress resistance and virulence of Riemerella anatipestifer CH-1 using a new unmarked gene deletion strategy[J]. Vet Microbiol. 2020 Aug;247:108730.
8. 6. Liu M, Huang M, Huang L, Biville F, Zhu D, Wang M, Jia R, Chen S, Zhao X, Yang Q, Wu Y, Zhang S, Huang J, Tian B, Chen X, Liu Y, Zhang L, Yu Y, Pan L, Ur Rehman M, Cheng A. New perspectives on Galleria mellonella larvae as a host model using Riemerella anatipestifer as a proof of concept [J]. Infect Immun, 2019, 23;87(8):e00072-19.
3. Main invention patent:
1. RpsL mutant gene of Riemerella anatipestifer and its application, national invention patent, authorization time: August 2019 Patent authorization No.: zl201610903474.6, Inventor: Liu Mafeng.
2. Method for efficiently deleting the gene of Riemerella anatipestifer, national invention patent, authorization time: October 2019 Patent authorization No.: zl201610905578.0, Inventor: Liu Mafeng.
3. A gene deletion attenuated strain of Riemerella anatipestifer and its construction method and application, national invention patent, authorization time: November 2019 Patent authorization No.: zl201710022087.6, Inventor: Liu Mafeng.
4. A method for rapidly replenishing the deleted gene of Riemerella anatipestifer, national invention patent, authorization time: December 2019 Patent authorization No.: zl20161111604.0, Inventor: Liu Mafeng.
5. Method and application of shuttle plasmid pLMF03 in interfering with the expression of target gene of Riemerella anatipestifer, national invention patent, authorization time: January 2020 Patent authorization No.: zl201610225412.4, Inventor: Liu Mafeng.